Fig. 1.
a Dietary AGE intake (dAGE) correlates negatively with MNC SIRT1 mRNA in older healthy subjects (n = 67). Baseline dietary AGE intake was estimated from 3-day food records and is expressed as AGE Eq/day. MNC SIRT1 mRNA levels were measured by RT-PCR. b Dietary AGE intake (dAGE) correlates positively with fasting serum CML (sCML) levels, based on CML ELISA. Analyses were based on the Pearson correlation coefficient