Table 1.
Baseline characteristics of the cross-section population
| Parameters | All | Women | Men | p* |
|---|---|---|---|---|
| N | 67 | 40 | 27 | |
| Age (years) | 70 ± 1 | 71 ± 1 | 68 ± 2 | 0.173 |
| BMI (kg/m2) | 26 ± 0.6 | 25 ± 0.7 | 28 ± 1.0 | 0.012 |
| Weight (kg) | 72 ± 2 | 65 ± 2 | 87 ± 3 | 0.000 |
| Waist circumference (cm) | 94 ± 2 | 88 ± 2 | 108 ± 4 | 0.000 |
| Systolic blood pressure (mmHg) | 127 ± 2 | 132 ± 3 | 125 ± 3 | 0.127 |
| Diastolic blood pressure (mmHg) | 69 ± 1 | 75 ± 2 | 67 ± 1 | 0.003 |
| Creatinine Clearance (ml/min) | 91 ± 3 | 88 ± 4 | 96 ± 6 | 0.262 |
| BUN (mg/dl) | 18 ± 0.6 | 18 ± 0.7 | 18 ± 1.0 | 0.718 |
| Serum albumin (g/dl) | 4.2 ± 0.04 | 4.2 ± 0.06 | 4.2 ± 0.04 | 0.560 |
| Triglycerides (mg/dl) | 96 ± 6 | 95 ± 7 | 99 ± 8 | 0.682 |
| Cholesterol (mg/dl) | 198 ± 4 | 205 ± 4 | 179 ± 6 | 0.001 |
| HDL cholesterol (mg/dl) | 66 ± 2 | 71 ± 2 | 54 ± 3 | 0.000 |
| LDL cholesterol (mg/dl) | 113 ± 3 | 116 ± 4 | 106 ± 5 | 0.121 |
| sCML (U/ml) | 9.2 ± 0.4 | 9.0 ± 0.5 | 9.5 ± 0.7 | 0.600 |
| Fasting blood glucose (mg/dl) | 81.5 ± 1 | 81 ± 1 | 83 ± 3 | 0.458 |
| Insulin (μU/ml) | 6.6 ± 0.4 | 6.4 ± 0.5 | 6.9 ± 0.9 | 0.640 |
| HOMA-IR | 1.30 ± 0.09 | 1.28 ± 0.09 | 1.38 ± 0.18 | 0.626 |
| Leptin (ng/ml) | 20 ± 2 | 21 ± 3 | 18 ± 3 | 0.554 |
| Adiponectin (μg/ml) | 8.7 ± 0.7 | 8.5 ± 0.8 | 9.1 ± 1.2 | 0.656 |
| Leptin/adiponectin | 4.2 ± 1 | 4.6 ± 1 | 3.4 ± 1 | 0.473 |
| sMG (nmol/ml) | 0.89 ± 0.03 | 0.89 ± 0.03 | 0.89 ± 0.05 | 0.927 |
| 8-isoprostane (pg/ml) | 152 ± 8 | 154 ± 11 | 147 ± 13 | 0.655 |
| VCAM1 (ng/ml) | 797 ± 34 | 810 ± 43 | 767 ± 57 | 0.556 |
| TNFα (pg/mg protein) | 8.5 ± 0.4 | 8.4 ± 0.5 | 8.7 ± 0.7 | 0.714 |
| RAGE (mRNA) | 356 ± 24 | 371 ± 31 | 322 ± 34 | 0.296 |
| AGER1 (mRNA) | 188 ± 13 | 192 ± 16 | 180 ± 24 | 0.678 |
| SIRT1 (mRNA) | 342 ± 20 | 364 ± 27 | 294 ± 21 | 0.047 |
| Caloric intake (kcal/d) | 1834 ± 95 | 1821 ± 106 | 1861 ± 198 | 0.861 |
| Protein intake (g/day) | 83 ± 6 | 77 ± 5 | 98 ± 14 | 0.165 |
| Carbohydrate intake (g/day) | 235 ± 15 | 225 ± 18 | 256 ± 28 | 0.345 |
| Fat intake (g/day) | 68 ± 4 | 68 ± 5 | 66 ± 7 | 0.760 |
| Saturated fat intake (g/day) | 21 ± 1 | 21 ± 2 | 22 ± 3 | 0.623 |
| AGE intake (Eq/day) | 12.4 ± 1.0 | 12.8 ± 1.0 | 11.5 ± 1.0 | 0.498 |
All values are expressed as mean ± SEM
*
p value reflects the difference between men and women as estimated by unpaired t test