Table 2.
Differences for selected biochemical parameters and BMI before and after intervention in each dietary group
| Parameter | Low-AGE diet
|
Regular AGE diet
|
p* | ||
|---|---|---|---|---|---|
| Mean | SEM | Mean | SEM | ||
| sCML (U/ml) | −3.71 | 1.03 | 1.87 | 1.05 | 0.002 |
| sMG (nmol/ml) | −0.28 | 0.07 | 0.18 | 0.10 | 0.002 |
| SIRT1 (mRNA, AU) | 92 | 52 | −189 | 62 | 0.003 |
| AGER1 (mRNA, AU) | −70 | 24 | 69 | 27 | 0.001 |
| RAGE (mRNA, AU) | −127 | 41 | 253 | 137 | 0.021 |
| p66shc (mRNA, AU) | −27 | 10 | 26 | 11 | 0.003 |
| 8-Isoprostane (pg/ml) | −48 | 11 | 48 | 20 | 0.002 |
| TNFα (pg/mg cell protein) | −2.1 | 1.6 | 3.2 | 0.8 | 0.013 |
| VCAM1 (pg/ml) | −270 | 92 | 182 | 46 | 0.002 |
| hsCRP (mg/l) | 1.3 | 1.4 | 0.4 | 0.4 | 0.582 |
| Leptin (ng/ml) | −4.2 | 3.5 | 4.5 | 4.4 | 0.162 |
| Adiponectin (ug/ml) | −0.96 | 1.4 | −0.34 | 1.1 | 0.744 |
| HOMA-IR | 0.04 | 0.44 | 0.14 | 0.15 | 0.834 |
| Triglycerides (mg/dl) | −10 | 7 | −6 | 7 | 0.683 |
| HDL (mg/dl) | −7 | 2 | 2 | 4 | 0.098 |
| LDL (mg/dl) | −5 | 5 | 0.1 | 4 | 0.479 |
| BMI | −0.43 | 0.27 | −0.29 | 0.25 | 0.722 |
Differences or deltas were calculated as last minus first visit under the index treatment
*
p statistical significant differences between deltas