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. Author manuscript; available in PMC: 2014 Oct 15.
Published in final edited form as: J Immunol. 2013 Sep 11;191(8):4348–4357. doi: 10.4049/jimmunol.1103621

Figure 5. Increased neutrophil entry to TDLNs is supported by CXCR2 and CXCL2, but not CXCL1.

Figure 5

(A) Colo26-HA tumor-bearing Cxcr2−/− or BALB/c mice were subjected to PDT and the number of neutrophils per TDLN was determined by flow cytometry at the indicated time points. (B – C) TDLNs were harvested at the indicated time points post PDT and a single-cell suspension was generated. The number of neutrophils per TDLN was analyzed by flow cytometry in the presence of (B) 100 μg anti-CXCL2 antibodies or (C) 100 μg anti-CXCL1 antibodies given intravenously immediately prior to PDT. Each group contains a minimum of 9 mice and the experiment was repeated twice. Error bars represent mean ± SEM. *P<0.02 to 0h; #P<0.02 to Isotype or BALB/c.