Table 3.

Distributions of research articles and clinical trial research across five neglected diseases in Africa

	Number of articles with at least one African author/million African DALY	Number of trials recruiting in Africa/million African DALY
Diarrhoeal diseases	9.1	0.2
Lower respiratory infections and meningitis	10.6	0.5
Malaria	59.7	6.6
HIV	53.6	4.5
Tuberculosis	82.8	4.1

Notes: To demonstrate how the distribution of R&D can be measured using different R&D indicators, numbers of African research articles and African clinical trials are related to African burden of disease for the five diseases with the highest burden of disease in Table 1. Numbers were calculated from Nwaka et al. (2010) (31).

DALYs=disability-adjusted life years.