Palladium particle sizes at different reaction times for the dehydrogenation of (A) 3-methylcyclohexanone and (B) 3-methylcyclohexenone at 5 min and 2 h. Reaction conditions: [ketone] = 2 M (1 mmol), [Pd(TFA)2] = 0.06 M (0.03 mmol), [2-Me2Npy] = 0.12 M (0.06 mmol), [TsOH] = 0.24 M (0.12 mmol), DMSO for VTotal of 0.5 mL, 1 atm O2, 80 °C.