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. Author manuscript; available in PMC: 2014 Jul 19.
Published in final edited form as: ACS Chem Biol. 2013 May 7;8(7):1519–1527. doi: 10.1021/cb400158t

Figure 5.

Figure 5

Effect of TIF1 mutations and rocaglamides on ATP hydrolysis. Assays were performed as described in the Methods in the presence of 0.5% DMSO (black), 10 µM ROC-N (white), or 50 µM silvestrol (gray). The % ATP hydrolysis is plotted as a ratio of 32P-Pi/(32P-ATP + 32P-Pi). A background value of 5 % Pi obtained in the absence of protein and RNA was subtracted from each value. n=3 ± SEM.

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