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. Author manuscript; available in PMC: 2013 Oct 13.
Published in final edited form as: Int Urogynecol J Pelvic Floor Dysfunct. 2008 Sep 19;20(1):19–25. doi: 10.1007/s00192-008-0723-7

Figure 5.

Figure 5

Pedigree showing autosomal dominant inheritance of S-POP phenotype. Mouse number 1385 was selected for breeding based on exhibition of the S-POP phenotype. Mouse 1385 may be homozygous for the S-POP mutation and if so we expect all of his progeny to develop prolapse. He was mated to two FVB female mice and two litters were produced. One male mouse was found moribund shortly after weaning. Of the eight females, 6 females are exhibiting S-POP at 4 months of age. Of the 8 surviving male mice, two have developed S-POP. The evaluation is based on external examination with comparison to wildtype animals.