Figure 1.

Detection of RAGE proteins in murine lung and pancreas. Western blots using two distinct anti-RAGE antibodies, R&D AF1179 and sc-8230, detected three and six RAGE proteins in murine lung and pancreas, respectively (A). Immunohistochemistry on pancreas tissue using the sc-8230 anti-RAGE antibody detected RAGE in acinar cells (B), in the islets of Langerhans (C), and in interstitial cells (D), while no staining was observed in the negative control when the primary antibody was omitted (E). Bar=20 micrometer.