Table 1.
Association between the mRNA levels of PHB1 and clinic-pathologic data in NSCLC patients
| Total (n = 55) | PHB1 mRNA levels | P | ||||
|---|---|---|---|---|---|---|
|
| ||||||
| Increased* (n = 37) | Not increased* (n = 18) | |||||
|
| ||||||
| No. | No. | % | No. | % | ||
| Gender | ||||||
| Male | 39 | 27 | 69.2 | 12 | 30.8 | 0.629 |
| Female | 16 | 10 | 62.5 | 6 | 37.5 | |
| Age | ||||||
| ≤ 60 | 37 | 24 | 64.9 | 13 | 35.1 | 0.585 |
| > 60 | 18 | 13 | 72.2 | 5 | 27.8 | |
| Subtype | ||||||
| Squamous-celled carcinoma | 16 | 9 | 56.3 | 7 | 43.8 | 0.302 |
| Adenocarcinoma | 34 | 25 | 73.5 | 9 | 26.5 | |
| Adenosquamous carcinoma | 5 | 3 | 60.0 | 2 | 40.0 | |
| Differentiation | ||||||
| Well | 21 | 10 | 47.6 | 11 | 52.4 | 0.015 |
| Poor and moderated | 34 | 27 | 79.4 | 7 | 20.6 | |
| Lymph node metastasis | ||||||
| Positive | 28 | 24 | 85.7 | 4 | 14.3 | 0.003 |
| Negative | 27 | 13 | 48.1 | 14 | 51.9 | |
| Distant metastasis | ||||||
| Positive | 6 | 4 | 66.7 | 2 | 33.3 | 0.973 |
| Negative | 49 | 33 | 67.3 | 16 | 32.7 | |
| Tumor size | ||||||
| ≤ 3 cm | 25 | 16 | 64.0 | 9 | 36.0 | 0.637 |
| > 3 cm | 30 | 21 | 70.0 | 9 | 30.0 | |
*
The increased folds of “> 2” were defined as “increased”, while the increased folds of “≤ 2” were defined as “not increased”.