Table 2.
Association between the protein levels of PHB1 with histopathologic features of NSCLC patients
| Total (n = 26) | PHB1 expression | P | ||||
|---|---|---|---|---|---|---|
|
| ||||||
| Increased (n = 22) | Not Increased (n = 4) | |||||
|
| ||||||
| No. | No. | % | No. | % | ||
| Gender | ||||||
| Male | 19 | 15 | 78.9 | 4 | 21.1 | 0.187 |
| Female | 7 | 7 | 100.0 | 0 | 0.0 | |
| Age | ||||||
| ≤ 60 | 19 | 16 | 84.2 | 3 | 15.8 | 0.925 |
| > 60 | 7 | 6 | 85.7 | 1 | 14.3 | |
| Subtype | ||||||
| Squamous-celled carcinoma | 15 | 12 | 80.0 | 3 | 20.0 | 0.188 |
| Adenocarcinoma | 10 | 9 | 90.0 | 1 | 10.0 | |
| Adenosquamous carcinoma | 1 | 1 | 100.0 | 0 | 0.0 | |
| Differentiation | ||||||
| Well | 8 | 5 | 62.5 | 3 | 37.5 | 0.037 |
| Poor and moderated | 18 | 17 | 94.4 | 1 | 5.6 | |
| Lymph node metastasis | ||||||
| Positive | 16 | 15 | 93.8 | 1 | 6.3 | 0.102 |
| Negative | 10 | 7 | 70.0 | 3 | 30.0 | |
| Distant metastasis | ||||||
| Positive | 4 | 4 | 100.0 | 0 | 0.0 | 0.354 |
| Negative | 22 | 18 | 81.8 | 4 | 18.2 | |
| Tumor size | ||||||
| ≤ 3 cm | 12 | 10 | 83.3 | 2 | 16.7 | 0.867 |
| > 3 cm | 14 | 12 | 85.7 | 2 | 14.3 | |