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. 2013 Oct 14;3:2932. doi: 10.1038/srep02932

Figure 6. The kinase activity of CDK5 was essential for its function via phosphorylation of FAK at Ser-732.

Figure 6

(a) immunoblotting analysis of expression of FAK and p-FAK S732 in MCF10A cells cultured without or with TGF-β1 after infection of shCDK5-1# or empty vector. (b) and (c) immunoblotting analysis of expression of CDK5, FAK, p-FAK Y397 and p-FAK S732 in MDA-MB-231 (b) and BT549 (c) cells after infection of shCDK5-1# or empty vector.