FIG. 6.

NeMo results for normal pressure hydrocephalus. (A) Illustrates the normalization process for the anterior (top row) and posterior (bottom row) hand-drawn regions of interest masks that indicate peri-ventricular WM hyperintensities. The left column is the lesion in original patient space superimposed on the patient's scan, the middle column is the lesion in MNI space superimposed on the normalized patient scan, and the right column is the lesion in MNI space superimposed on the template scan. The corresponding ChaCo scores are given in (B) for the anterior (top) and posterior (bottom) masks. Each of the 116 regions' centroids are a sphere (color coded by regional membership) whose size corresponds to the ChaCo of that region (larger spheres indicate more negative scores). (C) Shows the two masks' results in the same brain as to illustrate their inter-relationship.