Table 3.
Top 12 Combinations of Metrics Ranked by Day +4 Area under the Curve for Distinguishing between Injured and Sham Animals, the Corresponding Receiver Operating Characteristic Area under the Curve for Days −1, +1, and +4, the Optimal Cutoff Value for Dividing Injured and Sham Groups on Day +4 and the Day +4 Sensitivity and Specificity Using that Cutoff Value
|
|
Day −1 |
Day +1 |
Day +4 |
|||
---|---|---|---|---|---|---|---|
Metrics included | AUC | AUC | AUC | Cutoff | Sensitivity | Specificity | |
A | Sniffing Toy, Moving Toy, Lempel-Ziv Complexity, PDIAG, MPS | 0.63 | 0.95 | 0.96 | 2.5 | 100.0% | 85.7% |
B | Moving Toy, PDIAG, MPS | 0.63 | 0.96 | 0.95 | 2.8 | 75.0% | 100.0% |
C | Sniffing Toy, Moving Toy, Lempel-Ziv Complexity, T-maze Normal Time, T-maze Time at Old Food Location | 0.59 | 0.93 | 0.95 | 3.5 | 75.0% | 100.0% |
D | Sniffing Toy, Moving Toy, Lempel-Ziv Complexity, PDIAG, T-maze Normal Errors, MPS | 0.63 | 0.84 | 0.95 | 5.1 | 75.0% | 100.0% |
E | Moving Toy, Lempel-Ziv Complexity, PDIAG, T-maze Time at old food location, MPS | 0.61 | 1.00 | 0.93 | 4.6 | 75.0% | 100.0% |
F | Sniffing Toy, Moving Toy, Lempel-Ziv Complexity, PDIAG, T-maze Normal Time, T-maze Reversal Time, T-maze Time at old food location | 0.63 | 0.93 | 0.93 | 5.8 | 75.0% | 100.0% |
G | Sniffing Toy, Moving Toy, Lempel-Ziv Complexity, PDIAG, Beam Time, MPS | 0.63 | 0.93 | 0.93 | 5.9 | 75.0% | 100.0% |
H | Sniffing Toy, Moving Toy, Lempel-Ziv Complexity, T-maze Reversal Time, Beam Time | 0.61 | 0.93 | 0.93 | 4.3 | 75.0% | 100.0% |
I | Sniffing Toy, Moving Toy, MPS | 0.61 | 0.93 | 0.93 | 1.1 | 87.5% | 85.7% |
J | Sniffing Toy, Moving Toy, Lempel-Ziv Complexity, PDIAG, T-maze Normal Time, MPS | 0.61 | 0.89 | 0.93 | 5.7 | 75.0% | 100.0% |
K | Sniffing Toy, Moving Toy, Lempel-Ziv Complexity, PDIAG, T-maze Reversal Time, MPS | 0.61 | 0.89 | 0.93 | 6.6 | 75.0% | 100.0% |
L | Moving Toy, Lempel-Ziv Complexity, T-maze Reversal Time | 0.61 | 0.88 | 0.93 | 2.6 | 75.0% | 100.0% |
AUC, area under the curve; MPS, motor proficiency score.