TABLE 1.

Changes in steroidogenic metabolite secretion by H295R cells in response to forskolin stimulation and precursor feeding

	Steroidogenic metabolite, ng/4×105 cells/24 h
Treatment	Pre	Pro	17Pro	And	11Cor	Cor	Cos
Basal	Tr	37±12	Nd	317±21	Nd	724±25	12±4
Forskoline (F)	Tr	82±16*	21±4*	720±21*	8±1*	2,932±185*	82±8*
F+Cholesterol	Tr	251±45**	794±61**	1,851±181**	325±12**	3,635±148**	156±8**
F+Pregnenolone	Fd	358±21**	921±25**	1,583±53**	814±33**	3,840±99**	160±12**
F+Progesterone	Tr	Fd	1,809±49**	1,419±78**	2,722±246**	3,894±37**	103±21**
F+Deoxycorticosterone	Tr	107±16	71±47	748±25	Fd	3,692±361**	12±4

Nd, not detected; Tr, trace amount; Fd, precursor feeding.

^*Significantly different from control value.

^**Significantly different from forskolin value (P<0.05).