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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: J Immunol. 2013 Aug 23;191(7):3884–3895. doi: 10.4049/jimmunol.1301344

Figure 8. Cytokines considered inducers and regulators of IFNγ are concomitantly upregulated in the serum of IFrag−/− but not RAG−/− mice in response to Pneumocystis lung infection.

Figure 8

Comparative serum cytokine analysis was performed on IFrag−/− and RAG−/− mice at day 0, 7 10 and 16 post Pneumocystis lung infection using a multiplex ELISA-based assay to evaluate if other pro-inflammatory and IFNγ-regulatory cytokines are uniquely induced in IFrag−/− mice. Shown are comparative data for IFNγ (A), IL-12p70 (B), IL-18 (C), IL-1β (D), IL-15 (E) and IL-10 (F). Statistical analysis was performed using a 2-way ANOVA. Comparisons reflect differences between the groups at each individual time point. P values are marked as * p< 0.05, ** p<0.01, *** p<0.001.