Table 1.
NR1 expression in hibernating or inter-bout euthermic AGS braina
| Brain regions | Level of staining |
|---|---|
| Olfactory region | |
| Anterior olfactory nucleus (AO) | 2 |
| Main olfactory bulb | |
| Glomerular layer of olfactory bulb (Gl) | 1 |
| Periglomerular cell (Pg) | 1 |
| External plexiform layer olfactory bulb (EPl) | 1.5 |
| Mitral cell layer of olfactory bulb (Mi) | 2 |
| Internal plexiform layer olfactory bulb (Ipl) | 1 |
| Granular cell layer of olfactory bulb (Gro) | 1–1.5 |
| Cortex | |
| Piriform cortex (pir) | 3.5 |
| Frontal association cortex (FrA) and prelimbic cortex (PrL) | |
| Layer 1 | 0–0.5 |
| Layers 2–3 | 2.5 |
| Layer 4–6 | 2 |
| Parietal association cortex (PtA) and primary motor cortex (M1) | |
| Layer 1 | 0–0.5 |
| Layers 2–3 | 3.5 |
| Layer 4 | 2–2.5 |
| Layer 5 | 3–3.5 |
| Layer 6 | 2.5–3 |
| Hippocampus | |
| CA1 | |
| Stratum oriens (Or) | 1–1.5 |
| Pyramidal layer (Py) | 3.5–4 |
| Stratum radiatum (Ra) | 2.5 |
| Stratum lacunosum-moleculare (LM) | 1.5 |
| CA3 | |
| Stratum oriens (Or) | 1–1.5 |
| Pyramidal layer (Py) | 3–3.5 |
| Stratum lucidum (Lu) | 3 |
| Dentate gyrus | |
| Molecular layer (Mo) | 1.5 |
| Granular layer (Gr) | 3.5–4 |
| Polymorph layer (hilus) | 3–3.5 |
| Amygdala | |
| Posterolateral cortical amygdale nucleus (PLCo) | 2.5 |
| Posteromeidal cortical amygdale nucleus (PMCo) | 2.5 |
| Dorsal endopiriform nucleus (Den) | 1.5 |
| Lateral amygdaloid nucleus (La) | 2.5–3 |
| Basolateral amygaloid nucleus (BL) | 3 |
| Septum | |
| Medial septal nucleus (MS) | 2 |
| Lateal septal nucleus, dorsal (LSD) | 1 |
| Lateal septal nucleus, intermediate (LSI) | 1 |
| Nucleus of horizontal limb diagonal band (HDB) | 2 |
| Nucleus of vertical limb diagonal band (VDB) | 2 |
| Basal ganglia | |
| Caudate nucleus | 2–2.5 |
| Putamen | 3 |
| Nucleus accumbens core (Acbc) | 2 |
| Lateral global pallidum (LGP) | 2 |
| Ventral pallidum (VP) | 2 |
| Thalamus | |
| Lateral habenular nucleus (LHb) | 2 |
| Medial habenular nucleus (MHb) | 3.5 |
| Stria medullairs of thalamus (sm) | 0–0.5 |
| Paraventricular thalamic nucleus, posterior (PVP) | 3–3.5 |
| Intermediodorsal thalamic nucleus (IMD) | 2.5–3 |
| Centeral medial thalamic nucleus (CM) | 3 |
| Reuniens thalamic nucleus (Re) | 3 |
| Laterodorsal thalamic nucleus (LDV) | 2.5–3 |
| Ventral thalamic nuclear group (Vl, VM) | 2.5–3 |
| Ventral posterior thalamic neulear group (VPM, VPL) | 2.5–3 |
| Posterior thalamic nuclear group (Po) | 2.5–3 |
| Hypothalamus | |
| Lateral hypothalamic area (LH) | 1.5 |
| Magnocellular nucleus of lateral hypothamus | 2.5 |
| Dorsomedial nucleus, dorsal (DMD) | 2 |
| Perifornical nucleus (PeF) | 2 |
| Periventrical hypothalamic nucleus (Pe), neuropilar | 1.5 |
| Ventromed nucleus (VMH) | |
| Dorsomedial part | 2.5–3 |
| Ventrolateral part | 2 |
| Arcuate nucleus, medial part (ArcM) | 3.5 |
| Medial eminence (ME) | 3.5 |
| Suprachiasmatic nucleus (SCN) | 1 |
| Lateral preoptic area (LPO) | 0.5–1 |
| Supraopic nucleus (SO) | 1 |
| Midbrain | |
| Superficial gray layer of superior colliculus (SuG) | 2 |
| Optic nuclear layer of superior colliculus (OP) | 1 |
| Optic tract | 0 |
| Medial genic nucleus (MG) | 1.5 |
| Substantia nigra (SNR) | 1.5 |
| Commissural of superior colliculus (CSC) | 0.5 |
| Cerebral peduncle (CP) | 0.5 |
| Cerebellum | |
| Cerebellar cortex | |
| Molecular layer | 2 |
| Stellate cells | 1.5 |
| Granular layer | 2 |
| Purkinje cell body | 2.5 |
| Purkinje cell dendrities | 2–2.5 |
| Golgi cell | 1.5–2 |
| Brain stem | |
| Nucleus of the solitary trat, parvicellular part (SolPC) | 3–3.5 |
| Nucleus of the solitary tract, medial part (SolM) | 2 |
| Subpostrema dorsal (SubPD) | 3.5 |
| Hypoglossal (12) | 2.5–3 |
| Lateral reticular nucleus (LRt) | 2 |
| Lateral recticular nucleus, parvicell (LRtPC) | 1.5–2 |
| Superior paraolivary nucleus (SPO) | 1.5 |
| Medial vestibular nuclei, magnocellular part (MVeMC) | 2.5 |
| Facial nucleus (7) | 2 |
| Inferior olive (IO) | 2 |
| Dorsal motor nucleus of vagus (10) | 2 |
| Spinal trigeminal tract (sp5) | 0.5–1 |
| Spinal 5 nucleus (Sp5C, Sp5O) | 1–1.5 |
| Cervical spinal cord | |
| Lateral cervical nucleus (Latc) | 1.5 |
| Central cervical nucleus (CeCv) | 2 |
| Intermediomedial cell column (IMM) | 1.5 |
| Laminae I–III | 2 |
| Laminae IV–VIII | 1.5 |
| Motor neurons of laminae IX | 2.5 |
| Laminae X | 1.5 |
a
Level of staining is described using a relative scale from 0 to 4, in which 0 indicates the level seen in corresponding control sections and 4 indicates the densest staining. NR1 expression in hibernating and euthermic brain was compared systematically in hippocampus. Observations from other regions were made in brain sections from hAGS or ibeAGS.