Table I.

Clinicopathological characteristics grouped by non-urothelial or urothelial recurrence in 103 patients treated with an RNU and ipsilateral bladder cuff for UTUC.

		Non-urothelial recurrence			Urothelial recurrence
Characteristics	Total	Yes	No	P-value	Yes	No	P-value
Number of patients	103	32	71		38	65
Gender, n				0.819			0.511
Male	71	23	48		28	43
Female	32	9	23		10	22
Age, years				0.788			0.138
Mean	68.6	70.3	67.8		67.3	71.0
SD	10.1	9.3	10.4		10.2	9.4
Median	69.0	70.5	69.0		69.0	71.0
Range	23–91	51–91	23–87		23–87	54–91
Tumor side, n				0.400			0.221
Right	55	15	40		17	38
Left	48	17	31		21	27
BT at diagnosis, n				0.399			0.255
Yes	28	11	17		13	15
No	75	21	54		25	50
C-reactive protein (mg/ml), n				0.282			0.432
<0.3	60	16	44		23	37
≥0.3	43	16	27		15	28
Hemoglobin (mg/ml), n				0.599			0.614
≤NR	75	14	61		27	48
>NR	28	18	10		11	17
Histological type, n				0.166			0.865
Urothelial	92	24	68		32	60
Non-urothelial	11	8	3		6	5
Pathological grade, n				0.008			0.278
1	20	3	17		4	16
2	28	5	23		12	16
3	55	24	31		22	33
Adjuvant chemotherapy, n				0.508			0.756
Yes	12	5	7		5	7
No	91	27	64		33	55
Microvascular invasion, n				0.001			0.214
Absent	69	13	56		23	46
Present	34	19	15		15	19
Lymphatic invasion, n				0.005			0.654
Absent	71	17	54		24	47
Present	32	15	17		14	18
pT classification, n				0.001			0.209
pT0/pTis/pTa/pT1	43	6	37		15	28
pT2	13	2	11		2	11
pT3/pT4	47	24	23		21	26

RNU, radical nephroureterectomy; UTUC, upper tract urothelial carcinoma; BT, bladder tumor; NR, normal range; pT0/pTis/pTa/pT1, superficial; pT2, muscle invasive; pT3/pT4, non-organ defined.