Table 2. MS/MS data of protein spots up-regulated in PA FNA samples.
Spot no. | ID | Protein name | Gene name | Th | Obs | Matched peptides | Coverage(%) | Best ion score | Peptides identified | FV | p-value |
MW/pI | MW/pI | ||||||||||
777 | P02675 | Fibrinogen beta chain | FGB | 56/ 8.5 | 51/ 5.8 | 12 | 27 | 75.8 | (K)LESDVSAQmEYcR(T) | 2.8 | 6.480e−5 |
812 | Q13228 | Selenium-binding protein 1 | SELENBP1 | 52/5.9 | 48/5.6 | 11 | 29 | 94.3 | (R)NTGTEAPDYLATVDVDPK(S) | 3.6 | 0.002 |
1041 | Q9UK22 | F-box only protein 2 | FBOXO2 | 33/4.3 | 39/3.9 | 3 | 12 | 87.3 | (R)VLAALPAAELVQAcR(L) | 4.1 | 1.936e−5 |
1058 | P40121 | Macrophage-capping protein | CAPG | 38/5.8 | 39/5.6 | 5 | 26 | 59.6 | (R)QAALQVAEGFISR(M) | 3.0 | 8.584e−5 |
1221 | P04406 | Glyceraldehyde-3-phosphate dehydrogenase | GAPDH | 36/8.6 | 35/6.9 | 10 | 36 | 76.4 | (R)VPTANVSVVDLTcR(L) | 2.6 | 0.016 |
1239 | P04083 | Annexin A1 | ANXA1 | 39/6.6 | 34/5.8 | 18 | 45 | 102.5 | (R)KGTDVNVFNTILTTR(S) | 2.0 | 0.002 |
1254 | P02649 | Apolipoprotein E | APOE | 36/5.7 | 34/5.0 | 13 | 38 | 93.6 | (K)AYKSELEEQLTPVAEETR(A) | 3.9 | 2.383e−4 |
1335 | P09525 | Annexin A4 | ANXA4 | 36/5.8 | 32/5.2 | 11 | 29 | 110.1 | (K)AASGFNAmEDAQTLR(K) | 3.2 | 0.002 |
1343 | P67936 | Tropomyosin alpha-4 chain | TPM4 | 28/4.7 | 32/4.2 | 5 | 19 | 88.0 | (K)IQALQQQADEAEDR(A) | 2.1 | 0.004 |
1359 | P10768 | S-formylglutathione hydrolase | ESD | 31/6.5 | 32/5.8 | 3 | 16 | 63.0 | (K)KAFSGYLGTDQSK(W) | 2.4 | 0.002 |
1386 | P62258 | 14-3-3 protein epsilon | YWHAE | 29/4.6 | 31/4.1 | 9 | 33 | 83.7 | (K)KVAGmDVELTVEER(N) | 2.7 | 6.373e−4 |
1570 | P02647 | Apolipoprotein A-I | APOA1 | 31/5.6 | 28/4.5 | 10 | 36 | 101.4 | (K)LLDNWDSVTSTFSK(L) | 2.9 | 0.050 |
1700 | P32119 | Peroxiredoxin-2 | PRDX2 | 22/9.1 | 25/5.0 | 4 | 17 | 57.9 | (K)ATAVVDGAFKEVK(L) | 3.9 | 9.910e−5 |
1831 | P30086 | Phosphatidylethanolamine-binding protein 1 | PEBP1 | 21/7.0 | 24/6.1 | 4 | 23 | 53.6 | (K)GNDISSGTVLSDYVGSGPPK(G) | 2.0 | 0.025 |
1904 | P02511 | Alpha-crystallin B chain | CRYAB | 20/6.8 | 23/5.9 | 4 | 20 | 42.9 | (K)HFSPEELKVK(V) | 2.8 | 0.006 |
2046 | P00441 | Superoxide dismutase [Cu-Zn] | SOD1 | 16/5.7 | 21/5.3 | 2 | 16 | 35.1 | (R)HVGDLGNVTADK(D) | 2.8 | 1.363e−6 |
2276 | P62937 | Peptidyl-prolyl cis-trans isomerase A | PPIA | 18/7.7 | 19/6.0 | 5 | 36 | 66.0 | (R)ALSTGEKGFGYK(G) | 2.2 | 0.006 |
2294 | P62937 | Peptidyl-prolyl cis-trans isomerase A | PPIA | 18/7.7 | 19/6.3 | 3 | 22 | 70.5 | (R)VSFELFADKVPK(T) | 2.1 | 0.020 |
Th: theoretical; Obs: observed; FV: fold variation.