Table 2. The effect of curcumin and nanocurcumin on aldose reductase (AR) activity and sorbitol levels in rat lens.
Groups | AR | Sorbitol |
---|---|---|
Control | 52.93 ± 5.14 | 0.318 ± 0.060 a |
Diabetic (D) | 56.29 ± 3.79 | 2.671 ± 0.311b |
D + Curcumin | 53.46 ± 12.75 | 2.178 ± 0.162 c |
D + Nanocurcumin | 50.65 ± 4.21 | 1.589 ± 0.141 d |
D + Blank particles | 56.12 ± 14.77 | 2.442 ± 0.102 e |
p=0.938 | p=0.000 |
The data are mean ± SD (n=4). Different superscripts a, b, c, d, e) indicate data are significantly different from other groups. AR activity is expressed as µ moles NADPH oxidized/h/100 mg protein and sorbitol levels as µ moles/g lens.