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. 2013 Oct 14;8(10):e77317. doi: 10.1371/journal.pone.0077317

Table 1. Clinical characteristics of patients by statin group.

Statin users (n=44) No. (%) Statin non-users (n=282) No. (%) p-value
Demographics
Male sex 24 (54.5) 165 (58.5) .620
Age, median (IQR) years 64 (56-74) 57 (43-70) .006
Comorbid conditions
Chronic renal disease 18 (40.9) 63 (22.3) .008
Dialysis 6 (13.6) 17 (6) .067
Diabetes mellitus 22 (50) 67 (23.8) <.001
COPD 10 (22.7) 57 (20.2) .710
Chronic heart disease 25 (56.8) 61 (21.6) <.001
Cerebrovascular disease 8 (18.2) 40 (14.2) .505
Liver disease 2 (4.5) 52 (18.4) .021
Malignancy 16 (36.4) 111 (39.4) .692
Stem cell transplantation 2 (4.5) 20 (7.1) .394
Graft versus Host disease 0 (0) 8 (2.8) .273
Solid organ transplantation 6 (13.6) 26 (9.2) .364
HIV infection 0 (0) 14 (5) .131
Risk factors
ICU stay 20 (45.5) 132 (46.8) .802
Mechanical ventilation 18 (40.9) 103 (36.5) .636
Total parenteral nutrition 13 (29.5) 88 (31.2) .768
Vasopressor therapy 10 (22.7) 78 (27.7) .430
Previous surgery 23 (52.3) 112 (39.7) .120
Catheter placement (>48h) 41 (93.2) 248 (87.9) .360
Urinary catheter 32 (72.7) 130 (46.1) .002
Neutropenia 0 (0) 42 (14.9) .006
Chemotherapy 4 (9.1) 58 (20.6) .070
Radiotherapy 1 (2.3) 9 (3.2) .735
Corticosteroid therapy 15 (34.1) 133 (47.2) .122
Prior antibiotic therapy 41 (93.2) 256 (90.8) .801
Immunosuppressive therapy 10 (22.7) 65 (23) .953
Antifungal prophylaxis 2 (4.5) 35 (12.4) .120
Clinical characteristics (at candidemia diagnosis)
Fever 38 (86.4) 213 (75.5) .169
Hypotension 26 (59.1) 125 (44.3) .293
Vasopressor therapy requirement 16 (36.4) 83 (29.4) .402
Acute renal failure 18 (40.9) 81 (28.7) .127
Confusion 20 (45.5) 98 (34.8) .217
APACHE II, median (IQR) 18 (11-23) 16 (11-23) .365