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. 2013 Oct 14;8(10):e77160. doi: 10.1371/journal.pone.0077160

Figure 2. NHBE cells express CXCR4 but not CCR5 and HIV gp120 induces mucus through CXCR4.

Figure 2

(A): NHBE cell RNA was analyzed by qPCR for the expression of CXCR4 and CCR5 up to 40 cycles of amplification. (B): gp120LAV-induced mucus formation was determined in the presence or absence of CXCR4 inhibitor AMD3100 and CCR5 inhibitor maraviroc. (C): gp120-induced mRNA expression of MUC5AC and GABAARα2 was determined in the presence and absence of AMD3100 and maraviroc by qPCR analysis. Each experiment was repeated at least three times; bars represent mean ± SEM.