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. 2013 Oct 14;8(10):e77060. doi: 10.1371/journal.pone.0077060

Figure 8. Effect of ACSL4 expression on apoptosis in MCF-7 and SKBr3 cells.

Figure 8

Control and ACSL4-transfected MCF-7 cells were treated with varying doses of etoposide (A), triacsin C (B) or tamoxifen (C) for 48 hours and apoptosis measured as described in the text. For Panel D, control and ACSL4-transfected SKBr3 cells were treated with lapatinib for 48 hours and apoptosis measured as described in the text. Results shown are the means of triplicate determinations ± 1SD. Significance of the differences are A, p=0.027; B, p=0.012; C, p=0.005, D, p=0.008.