Table 6. Allele and genotype frequency for IS patients and healthy controls.

SNP			IS patients N = 287	HWE	Healthy controls N =  182	HWE	p value a dominantb	p value a recessivec	p value a allele de-pendent	Odds ratio (95% CI)
XbaI	Genotype	AA	33.5% (96)		33.5% (61)
		AG	49.1% (141)	0.89	50.5% (92)	0.56	0.7696	0.9880	0.3685	0.90 (0.54–1.48)**
		GG	17.4% (50)		15.9% (29)					0.99 (0.67–1.48)***
	Allele	A	58.0% (333)		58.8% (214)
		G	42.0% (241)		41.2% (150)				0.8671	0.97 (0.74–1.26)
PvuII	Genotype	TT	26.8% (77)		23.1% (42)
		TC	50.2% (144)	0.93	51.1% (93)	0.76	0.5572	0.4230	0.6046	1.17 (0.76–179)**
		CC	23.0% (66)		25.8% (47)					1.22 (0.79–1.88)***
	Allele	T	51.9% (298)		48.6% (177)
		C	48.1% (276)		51.4% (187)				0.3601	0.14 (0.87–1.48)

^aChi² test.

^bDominant model contrasts: for XbaI XX and Xx vs xx, for PvuII PP and Pp vs pp.

^cRecessive model contrasts: for XabI XX vs Xx and xx, for PvuII PP vs Pp and pp.