Fig. 7.

SEM images showing morphology of cells grown on the PDMS post microtextures that are 10 µm diameter, (a) 5 µm, (b) 10 µm, (c) 20 µm, and (d) 40 µm heights with the 10 µm, 20 µm, and 40 µm separation (IS=inter-spaces) between the posts. On Day 9, cells on post microtextures tended to attach next to the posts and spread between them while directing their processes towards posts and other cells (white arrows). Regardless post heights, the narrowest processes were observed on cells cultured on the post microtextures with 10 µm IS, in which individual cells tended to grow between and along the array of posts. On the smooth surfaces and post microtextures with 40 µm IS, cell bodies adopted a broad flattened shape and appeared to anchor to random locations on the surface as they migrated.