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. 2013 Oct 14;8(10):e76275. doi: 10.1371/journal.pone.0076275

Table 3. Outcome of treatment of tuberculosis in the Revised National Tuberculosis Control Programme in Malappuram District, Kerala, India, April 2010 to September 2011, by diabetes mellitus, demographic and clinical characteristics.

Characteristic Treatment outcome Relative risk
All Unfavourable Crude Adjusted
n % 95%CI 95%CI
Total 3,116 474 (100)
Sex
Female 1,001 93 (9)
Male 2,115 381 (18) 1.94 1.57–2.40 1.60 1.28–1.99
Age group
15–44 1,333 126 (9)
45+ 1,782 348 (19) 2.06 1.71–2.50 1.72 1.40–2.10
HIV status
Negative 2,536 344 (14)
Positive 36 8 (22) 1.64 0.88–3.04 1.93 1.06–3.50
Unknown 544 122 (22) 1.37–1.99 1.51 1.23–1.84
Site
Extra pulmonary 877 88 (10)
Pulmonary 2,239 386 (17) 1.72 1.38–2.14 1.30 0.99–1.72
Type of case
New 2,708 380 (14)
Re treatment 408 94 (23) 1.64 1.34–2.01 1.43 1.18–1.75
Sputum smear status
Negative/unknown 1,597 172 (18)
Positive 1,579 362 (12) 1.41 1.19–1.68 1.02 0.86–1.28
DOT in intensive phase
Regular 2940 405 (14)
Missed doses 176 69 (39) 2.85 2.32–3.49
Diabetes
No 2,127 288 (13)
Yes 667 113 (17) 1.25 1.02–1.53 0.99 0.81–1.21
Unknown 322 73 (23) 1.67 1.33–2.10 1.34 1.05–1.70
Diabetic control
Yes 103 9 (9)
No 137 24 (18) 2.00 0.97–4.13
Unknown 427 80 (19) 2.14 1.11–4.13

Unfavourable includes all outcomes other than cure or treatment completed; CI = Confidential interval; HIV =  Human immunodeficiency virus; DOT =  Directly observed treatment.