Table 1: Body of Evidence Examined According to Study Design.
| Study Design | Number of Eligible Studies |
|---|---|
| RCT Studies | |
| Systematic review of RCTs | 0 |
| Large RCT | 0 |
| Small RCT | 0 |
| Observational Studies | |
| Systematic review of non RCTs with contemporaneous controls | 1 |
| Non RCT with non-contemporaneous controls | 0 |
| Non RCT with contemporaneous controls | 1 |
| Non RCT with historical controls | 3a |
| Database, registry, or cross-sectional study | 0 |
| Case series | 0 |
| Retrospective review, modelling | 0 |
| Studies presented at an international conference | 0 |
| Expert opinion | 0 |
| Total | 5a |
Abbreviation: RCT, randomized controlled trial.
a
One study was reported in 2 papers.