Skip to main content
. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Semin Nephrol. 2013 Sep;33(5):448–456. doi: 10.1016/j.semnephrol.2013.07.006

Table 1.

List of studies showing differences in bone and mineral parameters by race.

Name of
Study
Objective Imaging
technique
Results of Study Comments
Pollock et al., 201173 Compare trabecular
and cortical bone
parameters at the
radius and tibia
between adolescent
white and black
females
Peripheral
quantitative
computed
tomography
(QCT)
Adolescent black females
have a stronger bone
profile at the tibia
compared to their white
counterparts.
Bone parameters
were similar at the
radius
Leonard et al., 201074 Effects of sex,
puberty, and race on
cortical bone
development
QCT Cortical bone parameters
were greater in blacks than
whites in Tanner stage 1–4
Barbour et al., 201148 Association of
Serum 25
hydroxyvitamin D
with bone
parameters in
Caucasian and
African men
QCT Positive linear trend noted
between increasing 25
hydroxyvitamin D and
bone parameters in
Caucasian but not in men
of African ancestry
In men of African
ancestry there was
threshold effect for
serum 25
hydroxyvitamin D
at approximately
18 ng/ml on
cortical thickness
in distal tibia.
Gutierrez et al., 20118 Racial differences in
bone mineral
density, parathyroid
hormone (PTH)
and vitamin D
Dual energy X-
ray
Absorptiometry
(Dxa)
Bone mineral density
decreased with decline in
25 hydroxyvitamin D in
Caucasians and Mexican
Americans but not in
African Americans
Data from study
suggests that PTH
secretion is
suppressed at a
lower vitamin D
level in African
Americans than in
Caucasians.
Hannan et
al., 200875
Relation between
Serum 25
hydroxyvitamin D
and bone mineral
density by race and
ethnic group
amongst men
DXA Positive correlation noted
between 25
hydroxyvitamin D and
bone mineral density in
white men but not in black
or Hispanic men
Cauley et al., 201149 Studying
association of 25
hydroxyvitamin D
to risk of fracture in
multiethnic women
Not applicable Low 25 hydroxyvitamin D
levels were associated with
higher risk of fracture in
white women but not in
black women
Study implicated
that the ideal level
of 25
hydroxyvitamin D
for skeletal health
may be different
for white and black
women.
Wetzsteon et al, 200976 Ethnic differences
in bone parameters
in childhood
QCT African American and
Hispanic children have
greater bone strength than
white children
Study suggested
that ethnic
differences in bone
strength emerge in
childhood
Peacock et al., 200977 Racial and sexual
differences of bone
parameters at the
femur
CT, DXA American blacks have
higher bone density than
American whites at the
femur
Chen et al, 201178 Relationship
between African
admixture and hip
geometry amongst
post-menopausal
women
DXA Greater African admixture
is correlated with better
bone density and hip
structure in black than
white post-menopausal
women