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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Biomaterials. 2013 Sep 27;34(38):10209–10216. doi: 10.1016/j.biomaterials.2013.08.076

Fig. 1.

Fig. 1

In vitro polyplex-mediated NIS gene delivery. Uptake kinetics of 125I in murine Cloudman melanoma М3 cells transfected with NIS gene after 24 hours of incubation with polyplexes (a) and NIS gene expression kinetics in M3 cells transfected with polyplexes and measured by 125I uptake after 1 h of incubation with 125I (b). 125I accumulation in М3 cells at 48 hours after NIS transfection and 1 h of incubation with 125I with targeted (PEI-PEG-MC1SP/DNA) and non-targeted (PEI-PEG/DNA) polyplexes as well as block of iodide uptake in transfected cells by addition of sodium perchlorate (c). Values are means ± SD. *p < 0.001.