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. 2013 Oct 11;54(10):6675–6685. doi: 10.1167/iovs.13-12550

Figure 3.

Figure 3

In the absence of kl structural proteins are decreased. All IHC representative images are from 7-week-old wild-type or knockout mouse retina. White bars denote wild-type and grey bars denote knockout quantification. (A) Representative active-caspase 3 expression in retina. Control E13 mouse embryo tissue was processed in parallel and imaged using identical settings. (B) Representative GFAP IHC images and quantification. Quantification of GFAP signal in GCL was conducted across multiple retinas at 7 weeks (n = 5 per group, ±SEM, significance determined by Student's t-test: ***P < 0.0001). (C) Representative neurofilament IHC images and quantification. Quantification of neurofilament signal in OPL was conducted across multiple retinas at 7 weeks (n = 4 per group, ±SEM). (D) Representative Thy1.2 IHC images and quantification. Quantification of Thy1.2 signal in GCL was conducted across multiple retinas at 7 weeks (n = 4 per group, ±SEM).