Table 1. Characteristics of Included Studies for the In-Hospital Post-Stent Thrombosis Mortality and Myocardial Infarction Meta-Analyses.
| Author, Year (N STs) | Data Recording | Inclusion Criteria | Stent Type | Country of Conduct | Inclusion Years | Definition of ST | Timing of ST | APT at ST Diagnosis | Funding |
|---|---|---|---|---|---|---|---|---|---|
| Armstrong 2012 (N=7,315) | R | Patients in The CathPCI Registry presenting with a ST and ACS (64% presented with STEMI) | DES=56%; BMS=23%; Unknown=21% | >100 centers in the United States | 2009-2010 | Definite | EST=20%; LST=19%; VLST=61% | NR | NR |
| Chechi 2008 (N=92) | R | Patients presenting with STEMI deemed a result of ST | BMS=24%; DES=76% | 1 center in Italy | 2004-2007 | Definite | EST=64%; LST=15%; VLST=21% | DAPT=67% | NR |
| Daemen 2007 (N=152) | Unclear | Patients undergoing SES or PES implantation and developing ST (45% presenting with MI) | DES=100% | 2 centers in the Netherlands and Switzerland | 2002-2005 | Definite | EST=60%; LST/VLST=40% | DAPT=61% | Academic |
| De la Torre-Hernandez 2008 (N=301) | P | Any patients presenting with ST (37% presented with STEMI) | DES=100% | 20 centers in Spain | 2002-2007 | Definite | AST=8%; SAST=42%; LST=50% | DAPT=68.4% | NR (not Industry) |
| Del Pace 2010 (N=41) | R | Consecutive patients presenting with ST (39% presented with STEMI, 78% with acute MI) | BMS=29%; DES=71% | 1 center in Italy | 2005-2006 | Angiographically or autopsy confirmed with ACS or sudden cardiac death (all cases were confirmed) | AST=12%; SAST=56%; LST/VLST=32% | DAPT=80% | NR |
| Ergelen 2010 (N=118) | R | Patients presenting with STEMI deemed a result of ST | NR | 1 center in Turkey | 2003-2008 | Definite | SAST=35%; LST=31%; LST=35% | NR | None |
| Lee 2010 (N=30) | Unclear | Patients presenting with VLST and acute MI and undergoing IVUS (78% presented with STEMI) | BMS=23%; DES=77% | 1 center in South Korea | 2004-2009 | Definite | VLST=100% | DAPT=7% | Foundation |
| Lemesle 2009 (N=91) | R | Patients previous undergoing DES implantation and presenting with ST (75% presented as STEMI, 100% ACS) | DES=100% | 1 center in the United States | 2003-2008 | Definite | NR | NR | NR |
| Pinto Slottow 2008 (N=84*) | R | Patients experiencing a ST any time after PCI (38% experiencing a MI during ST admission) | DES=100% | 1 center in the United States | 2003-2007 | Definite | EST=62%; LST=20%; VLST=18% | ASA=90%; CLO=82% | NR |
| Reynolds 2002 (N=26) | R | All patients presenting with ST and complete billing records | BMS=100% | 1 center in the United States | 1998-2000 | Angiographically confirmed | SAST=100% | NR | Industry |
| van Werkum 2009 (N=431) | I | Consecutive patients presenting with ST | BMS=62%;DES=35%; Both:4% | 3 centers in the Netherlands | 2004-2007 | Definite | AST=33%; SAST=41%; LST=13%; VLST=13% | ASA=87%; CLO=69% | Industry |
| Wenaweser 2005 (N=95) | R | All patients presenting with ST and undergoing emergency PCI | BMS=100% | 1 center in Switzerland | 1995-2003 | Definite | AST=11%; SAST=64%; LST=25% | CLO/TIC=76% | NR |
| Yeo 2011 (N=165**) | P/R | Patients presenting with ST (63% presenting with STEMI, 91% with MI) | NR | Multiple centers in the United States (California) | 2005-2010 | Definite | AST=4%; SAST=22%; LST=18%; VLST=50% | DAPT=41% | NR |
ACS=acute coronary syndrome; APT=antiplatelet therapy; ASA=aspirin; AST=acute stent thrombosis; BMS=bare metal stent; CLO=clopidogrel; DAPT=dual antiplatelet therapy; DES=drug-eluting stent; EST=early stent thrombosis; I=indeterminate; IVUS=intravascular ultrasound; LST=late stent thrombosis; MI=myocardial infarction; N=number of stent thromboses; NR=not reported; P=prospective; PCI=percutaneous coronary intervention; R=retrospective; SAST=sub-acute stent thrombosis; ST=stent thrombosis; STEMI=ST-segment elevation myocardial infarction; TIC=ticlopidine; VLST=very late stent thrombosis
*83 patients had 84 Definite STs; ** 153 patients had 165 Definite STs