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. 2013 Oct 15;8(10):e76496. doi: 10.1371/journal.pone.0076496

Table 1. Clinico-biological characteristics of patients and tumors.

Characteristics Training set (n=109) Validation set (n=105)
Age (years)
Means (min-max) 55.6 (36-75) 54.2 (40-69)
>50 74 (68%, 95%CI : 59%-77%) 68 (65%, 95%CI : 56%-74%)
<50 35 (32%, 95%CI : 23%-41%) 37 (35%, 95%CI : 26%-44%)
Size
T1 77 (71%, 95%CI :62%-79%) 77 (73%, 95%CI : 65%-82%)
T2 32 (29%, 95%CI : 20%-38%) 28 (27%, 95%CI : 19%-35%)
Elston-Ellis grade
I 63 (58%, 95% CI:49%-67%) 48 (46%, 95% CI : 36%-55%)
II 35 (32%, 95%CI:23%-41%) 41 (39%, 95%CI : 30%-48%)
III 9 (8%, 95%CI :3%-13%) 16 (15, 95%CI : 8%-22%)
Missing values 2 (2%) 0
Vascular invasion
Yes 10 (9%, 95%CI:4%-14%) 20 (19%, 95%CI :12%-26%))
ER status (IHC)
Positive 109 (100%) 105 (100%)
PR status (IHC)
Positive 83 (76%, 95%CI:68%-84%) 80 (76%, 95%CI:68%-84%)
KI67
< 14% nd 47 (45%, 95%CI:36%-55%)
> 14% nd 58 (55%, 95%CI:46%-64%)
Genomic grade
GGI 1 nd 56 (60%, 95%CI:50%-69%)
GGI 3 nd 38 (40%, 95%CI:30%-49%)
Undetermined nd 11 (10.5%)

Min: minimum; max: maximum. GG: genomic grade; ER: estrogen receptors; PR: progesterone receptor; 95%CI: Confidence Interval.