Table 3. Univariate and multivariate analyses for disease free-interval in the validation set.

Variables	Univariate analysis		Multivariate analysis
	Relative Risk (95% CI)	p	Relative Risk (95% CI)	p
Age <=50 vs >50 years	0.94 (0.45-1.98)	0.873
Pathological size >20mm vs <=20mm	1.11 (0.42-2.92)	0.827
Grade II/III vs I	2.12 (0.99-4.5)	0.052	1.39 (0.52-3.70)	0.515
PR status Negative vs Positive	0.9 (0.38-2.1)	0.805
Vascular invasion Yes vs No	1.36 (0.55-3.36)	0.512
KI67(IHC) >14 vs < 14%	2.57 (1.16-5.68)	0.020	1.39 (0.48-4.08)	0.544
Genomic Grade GG3 vs GG1	2.59 (1,17-5.73)	0.019	1.16 (0.39-3.48)	0.788
IHC3 score (continuous)	1.01 (1.00-1.01)	0.204
Number of Breakpoints >34 vs <34	3.7 (1.73-7.92)	<0.001	3.47 (1.29-9.31)	0.014

vs: versus.