Table 4. Multivariable Models with Peripheral and LA Blood Levels of sICAM-1 as the Dependent Variable.
Study population |
PAF group |
PeAF group |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Peripheral |
LA |
Peripheral |
LA |
Peripheral |
LA |
|||||||
sICAM-1 |
sICAM-1 |
sICAM-1 |
sICAM-1 |
sICAM-1 |
sICAM-1 |
|||||||
Exp β | P value | Exp β | P value | Exp β | P value | Exp β | P value | Exp β | P value | Exp β | P value | |
EATtotal /10 cm3 | 1.010 | 0.34 | 1.008 | 0.47 | 0.999 | 0.97 | 1.003 | 0.88 | 1.018 | 0.09 | 1.013 | 0.24 |
EATatrial /10 cm3 | 1.016 | 0.48 | 1.016 | 0.49 | 0.983 | 0.72 | 0.994 | 0.91 | 1.038 | 0.07 | 1.032 | 0.13 |
EATventricular /10 cm3 | 1.019 | 0.32 | 1.012 | 0.52 | 1.008 | 0.84 | 1.012 | 0.75 | 1.026 | 0.18 | 1.014 | 0.50 |
LA-ESO /mm | 1.052 | 0.04 | 1.042 | 0.10 | 1.114 | 0.05 | 1.103 | 0.09 | 1.036 | 0.11 | 1.026 | 0.27 |
LA-ThA /mm | 1.052 | 0.01 | 1.042 | 0.04 | 1.083 | 0.02 | 1.080 | 0.02 | 1.030 | 0.23 | 1.012 | 0.64 |
LA-PA /mm | 0.993 | 0.64 | 0.978 | 0.14 | 0.964 | 0.13 | 0.950 | 0.04 | 1.029 | 0.10 | 1.012 | 0.51 |
IAS /mm | 0.999 | 0.95 | 0.999 | 0.98 | 0.993 | 0.80 | 0.999 | 0.97 | 1.011 | 0.65 | 1.000 | 0.98 |
RAVG /mm | 1.003 | 0.80 | 1.004 | 0.74 | 0.988 | 0.53 | 0.992 | 0.69 | 1.015 | 0.31 | 1.013 | 0.39 |
LAVG /mm | 1.018 | 0.23 | 1.021 | 0.17 | 1.012 | 0.64 | 1.027 | 0.32 | 1.022 | 0.17 | 1.015 | 0.37 |
AIVG /mm | 1.030 | 0.18 | 1.027 | 0.23 | 1.034 | 0.31 | 1.029 | 0.39 | 1.044 | 0.17 | 1.042 | 0.20 |
Models were adjusted for BMI and LA volume. As the dependent variable was log-transformed, the β coefficients were exponentially transformed. Exponential transformation of β coefficients (Exp β) implies an interpretation on a multiplicative scale. The level of sICAM1 changes by 100*(Exp β-1) % for a one unit increase in each EAT variable.
Abbreviations: AIVG, anterior interventricular groove; EAT, epicardial adipose tissue; EATatrial, atrial EAT; EATventricular, ventricular EAT; IAS, interatrial septum; LA-ESO, periatrial epicardial fat located between the mid left atrium and esophagus; LA-PA, periatrial epicardial fat located between mid left atrium and pulmonary artery; LA-ThA, periatrial epicardial fat located between the mid left atrium and thoracic aorta; LAVG, left atrioventricular groove; PAF, paroxysmal atrial fibrillation; PeAF, persistent AF; RAVG, right atrioventricular groove.