Table 5. Comparison of various parameters in glomerular filtration stages of chronic kidney disease in type 2 diabetes patients (n = 85).
| G1 | G2 | G3 | G4 | Total | Kruskal-Wallis | |
| Number (male/female) | 9 (6/3) | 42 (22/20) | 29 (19/10) | 5 (2/3) | 85 (49/36) | |
| Age (years) | 51.9±13.9 | 62.9±10.3 | 66.5±9.2 | 59.6±15.3 | 62.9±11.3 | 0.647 |
| BMI (kg/m2) | 27.6±8.1 | 25.1±4.6 | 24.1±3.1 | 22.6±2.2 | 24.9±4.6 | 0.155 |
| SBP (mmHg) | 129.7±13.8 | 127.6±17.3 | 124.0±19.1 | 120.2±11.1 | 126.2±17.3 | 0.640 |
| DBP (mmHg) | 76.5±13.8 | 74.6±8.0 | 69.5±12.4 | 59.4±9.2 | 72.2±11.1 | 0.006 |
| HbA1c (%) | 7.54±0.79 | 7.27±0.83 | 7.40±0.94 | 6.68±0.82 | 7.31±0.87 | 0.323 |
| Total protein (g/L) | 70.4±3.7 | 70.9±4.4 | 67.6±6.2 | 63.0±5.0 | 69.3±5.44 | 0.002* |
| Albumin (g/L) | 41.4±4.6 | 42.3±2.9 | 38.3±6.6 | 33.4±5.0 | 40.4±5.3 | 1.10×10−4 ** |
| Cr (µmol/L) | 60.9±16.0 | 65.9±11.6 | 115.7±40.7 | 227.1±88.2 | 91.9±52.3 | 1.89×10−17 ** |
| UN (µmol/L) | 5.5±2.2 | 5.8±1.6 | 8.6±2.7 | 14.6±5.1 | 7.3±3.3 | 9.85×10−12 ** |
| Uric acid (µmol/L) | 329.1±39.5 | 312.8±74.4 | 388.7±82.6 | 391.4±99.8 | 344.6±83.1 | 6.59×10−4 ** |
| T-Cho (mmol/L) | 5.11±0.96 | 4.97±0.89 | 5.06±1.02 | 4.52±1.39 | 4.99±0.97 | 0.695 |
| TG (mmol/L) | 2.04±1.30 | 1.68±1.06 | 1.95±1.57 | 1.58±0.63 | 1.81±1.26 | 0.487 |
| HDL-C (mmol/L) | 1.25±0.26 | 1.44±0.37 | 1.32±0.41 | 1.45±0.51 | 1.38±0.39 | 0.427 |
| LDL-C (mmol/L) | 2.96±0.95 | 2.79±0.67 | 2.83±0.92 | 2.28±0.87 | 2.79±0.80 | 0.740 |
| eGFR (mL/min) | 96.2±15.6 | 74.8±8.1 | 44.4±9.2 | 20.6±8.3 | 63.5±22.4 | 1.16×10−30 ** |
| ACR (mg/gCr) | 179.7±451.6 | 108.3±227.7 | 824.5±0.80 | 1484±1168 | 441.2±812 | 1.09×10−5 ** |
| Fetuin-A (ng/gCr) | 0.39±0.39 | 0.49±0.45 | 1.25±1.18 | 1.34±0.80 | 0.79±0.87 | 3.89×10−4 ** |
| α1-microglobulin (µg/gCr) | 3.74±4.26 | 4.94±4.92 | 11.90±11.04 | 30.32±29.93 | 8.68±11.74 | 2.49×10−6 ** |
| Orosomucoid (ng/gCr) | 22.5±11.4 | 19.7±14.8 | 62.7±84.3 | 84.4±69.4 | 38.5±57.0 | 2.21×10−3 ** |
BMI, body mass index; SBP, Systolic Blood Pressure; DPB, Diastolic Blood Pressure; Cr, serum creatinine; UN, serum urea nitrogen; T-Cho, Total cholesterol; TG, Triglyceride; HDL-C, HDL cholesterol; LDL-C, LDL cholesterol; eGFR, estimated glomerular filtration ratio; ACR, albumin/creatinine ratio;
*
p<0.05;
**
p<0.01.