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. 2013 Oct 15;8(10):e75578. doi: 10.1371/journal.pone.0075578

Table 1. Linear model results for secreted and nuclear proteins at day 5.

SECRETOME NUCLEAR
Polysomal RNA Polysomal RNA
logFC Inline graphic Inline graphic Inline graphic logFC Inline graphic Inline graphic Inline graphic
Inline graphic - - Inline graphic Inline graphic - - Inline graphic
Inline graphic miR-130a - Inline graphic Inline graphic miR-185* - Inline graphic
Inline graphic miR-130b - Inline graphic Inline graphic miR-20b* - 0.175
Inline graphic miR-130b miR-558 Inline graphic Inline graphic miR-16-2* miR-185* Inline graphic

Results for applying linear models to the data at day Inline graphic secreted and nuclear proteins. Both RNA fractions are considered. For each subtable (e.g. secretome-polysomal) the first row shows the results for a linear model without considering microRNA effect (the standard model: Inline graphic vs. Inline graphic). The 2nd and 3rd row represent the values for univariate models, including the effect of only one miRNA. We selected the two most significant miRNAs. The last row shows the (multivariate) best model as determined by the BIC value. In several cases the best model is not multivariate, especially since BIC penalizes the number of parameters.

means a significance level of Inline graphic.