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. 2013 Oct 15;8(10):e75541. doi: 10.1371/journal.pone.0075541

Table 2. All analysed sentences and their classification.

Sentence Classification
belongs to the 40s cdc5-associated complex (or cwf complex), a spliceosome sub-complex reminiscent of a late-stage spliceosome composed of the u2, u5 and u6 snrnas and at least brr2, cdc5, cwf2, cwf3, cwf4, cwf5, cwf6, cwf7, cwf8, cwf9, cwf10, cwf11, cwf12, cwf13, cwf14, cwf15, cwf16, cwf17, cwf18, cwf19, cwf20, cwf21, cwf22, cwf23, cwf24, cwf25, cwf26, cwf27, cwf28, ist3, lea1, msl1, prp5, prp10, prp12, prp17, prp22, sap61, sap62, sap114, sap145, slu7, smb1, smd1, smd3, smf1, smg1 and syf2. Inconsistent
the light chain is composed of three structural domains: a large globular n-terminal domain which may be involved in binding to kinesin heavy chains, a central alpha-helical coiled-coil domain that mediates the light chain dimerization; and a small globular c-terminal which may play a role in regulating mechanochemical activity or attachment of kinesin to membrane-bound organelles (by similarity). Erroneous
the biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: 1) endoglucanases which cut internal beta-1,4-glucosidic bonds; 2) exocellobiohydrolases that cut the dissaccharide cellobiose from the nonreducing end of the cellulose polymer chain; 3) beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose. Inconsistent
in the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (krtap), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. Inconsistent
the beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating g protein inhibition and controlling the alpha-1 subunit membrane targeting (by similarity). Erroneous
interacts with the c-terminal of peptidylglycine alpha-amidating monooxygenase (pam) and may act as part of a signal transduction system linking the catalytic domains of pam in the lumen of the secretory pathway to cytosolic factors regulating the cytoskeleton and signal transduction pathways. Erroneous
The modification is dependent on dna and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from dna damage (by similarity). Erroneous
adenosylhomocysteine is a competitive inhibitor of s-adenosyl-l-methinine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine (by similarity). Inconsistent
component of the multisynthetase complex which is comprised of a bifunctional glutamyl-prolyl-trna synthetase, the monospecific isoleucyl, leucyl, glutaminyl, methionyl, lysyl, arginyl, and aspartyl-trna synthetases as well as three auxiliary proteins, p18, p48 and p43 (by similarity). Erroneous
self; 2; ebi-311928, ebi-311928; p03949:abl-1; 4; ebi-311928, ebi-2315883; q17539:c01b10.8; 5; ebi-311928, ebi-311920; q95qi7:daf-3; 2; ebi-311928, ebi-326363; q09248:dnc-2; 2; ebi-311928, ebi-316282; q09975:lys-8; 2; ebi-311928, ebi-313861; q21831:snfc-5; 2; ebi-311928, ebi-360213; Erroneous
the n-terminal of the protein extends into the stroma where it is involved with adhesion of granal membranes and photoregulated by reversible phosphorylation of its threonine residues; both are believed to mediate the distribution of excitation energy between photosystems i and ii. Inconsistent
the modification is dependent on dna and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from dna damage. Erroneous
the iicd domains contain the sugar binding site and the transmembrane channel; the iia domain contains the primary phosphorylation site (the donor is phospho-hpr); iia transfers its phosphoryl group to the iib domain which finally transfers it to the sugar (by similarity). Too Many Results
adenosylhomocysteine is a competitive inhibitor of s-adenosyl-l-methinine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine. Inconsistent
this delta-9 desaturase is a terminal component of the liver microsomal stearyl-coa desaturase system, that utilizes o(2) and electrons from reduced cytochrome b(5) to catalyze the insertion of a double bond into a spectrum of fatty acyl-coa substrates (by similarity). Inconsistent
in the absence of mercury merr represses transcription by binding tightly to the mer operator region; when mercury is present the dimeric complex binds a single ion and becomes a potent transcriptional activator, while remaining bound to the mer site (by similarity). Erroneous
chemotactic-signal tranducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation. Inconsistent
activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via g-protein coupled receptor (gpcr) occupancy by ligands such as bombesin or lysophosphatidic acid, or via ldl receptor occupancy. Erroneous
laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end (by similarity). Erroneous
psi is a plastocyanin-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor p700 chlorophyll pair to the spectroscopically characterized acceptors a0, a1, fx, fa and fb in turn (by similarity). Erroneous
involved in protection of chromosomal dna from damage under nutrient-limited and oxidative stress conditions. Inconsistent
belongs to the cold-shock domain (csd) family. Too Many Results
p35415:prm; 1; ebi-86215, ebi-133215; Erroneous
composed of 14 different subunits. Possibly Erroneous
proteins that associate with the core dimer include three families of regulatory subunits b (the r2/b/pr55/b55, r3/b″/pr72/pr130/pr59 and r5/b′/b56 families), the 48 kda variable regulatory subunit, viral proteins, and cell signaling molecules (by similarity). Inconsistent
type i restriction and modification enzymes are complex, multifunctional systems which require atp, s-adenosyl methionine and mg(2+) as cofactors and, in addition to their endonucleolytic and methylase activities, are potent dna-dependent atpases (by similarity). Inconsistent
3-beta-hydroxy-delta(5)-steroid + nad(+) = 3-oxo-delta(5)-steroid + nadh (acts on 3-beta-hydroxyandrost-5-en-17-one to form androst-4-ene-3,17-dione and on 3-beta-hydroxypregn -5-en-20-one to form progesterone). Accurate
udp-n-acetyl-d-glucosamine + n-acetyl-beta-d-glucosaminyl-1,2-alpha-d-mannosyl-1,3(6)-(n-acetyl-beta-d-glucosaminyl-1,2-alpha-d-mannosyl,1,6(3))-beta-d-mannosyl-1,4-n-acetyl-beta-d-glucosaminyl-r = udp + n-acetyl-beta-d-glucosaminyl-1,2-(n-acetyl-beta-d-glucosaminyl-1,6)-1,2-alpha-d-mannosyl-1,3(6) -(n-acetyl-beta-d-glucosaminyl-1,2-alpha-d-mannosyl-1,6(3))-beta-d-mannosyl-1,4-n-acetyl-beta-d-glucosaminyl-r. Erroneous
in e.coli rnase h participare in dna replication; it helps to specify the origin of genomic replication by suppressing initiation at origins other than the locus oric; along with the 5–′3éxonuclease of pol1, it removes rna primers from the okazaki fragments of lagging strand symthesis; and it defines the origin of replication for cole1-type plasmids by specific cleavage of an rna preprimer. Inconsistent
thoracic aortic aneurysms and dissections are primarily associated with a characteristic histologic appearance known as m´Inline graphicedial necrosisór érdheim cystic medial necrosisín which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance. Erroneous
component of the cleavage and polyadenylation specificity factor (cpsf) complex that play a key role in pre-mrna 3–′end formation, recognizing the aauaaa signal sequence and interacting with poly(a) polymerase and other factors to bring about cleavage and poly(a) addition (by similarity). Inconsistent
there are two operons: the xylcab operon is responsible for the upper metabolic pathway from toluene to aromatic carboxylic acids, & the xyldlefg operon is required for the lower catabolic pathway from aromatic carboxylic acids to compounds that enter the trycarboxylic acid cycle. Erroneous
hh is characterized by abnormal intestinal iron absorption and progressive increase of total body iron, which results in midlife in clinical complications including cirrhosis, cardiopathy, diabetes, endocrine dysfunctions, arthropathy, and susceptibility to liver cancer. Inconsistent
prp is found in high quantity in the brain of humans and animals infected with the degenerative neurological diseases kuru, creutzfeldt-jacob disease (cjd), gerstmann-straussler syndrome (gss), scrapie, bovine spongiform encephalopathy (bse), etc. to other prp. Accurate
involved in the atp-dependent selective degradation of cellular proteins, the maintenance of chromatin structure, the regulation of gene expression, the stress response, and ribosome biogenesis (by similarity). Erroneous
coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in cunjunction with another protein (s300-ii) stimulates initiation of transcription. Inconsistent
the lys-124 ubiquitination also modulates the formation of double-strand breaks during meiosis and is a prerequisite for and dna-damage checkpoint activation (by similarity). Erroneous
the export to cytoplasm depends on the interaction with a 14-3-3 chaperone protein and is due to its phosphorylation at ser-259 and ser-498 by camk (by similarity). Erroneous
the sigma factor is an initiation factor that promotes attachment of the rna polymerase to specific initiation sites and then is released (by similarity). Too Many Results
hydrolysis of 1,4-alpha-d-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains. Accurate
the resulting products may subsequently be converted to the corresponding alcohols that are incorporated into lignins (by similarity). Erroneous
involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. Inconsistent
s-adenosyl-l-methionine + magnesium protoporphyrin = s-adenosyl-l-homocysteine + magnesium protoporphyrin monomethyl ester. Erroneous
component of the coat surrounding the cytoplasmic face of coated vesicles located at the golgi complex (by similarity). Accurate
hsp82 is an essential protein that is required by cells in higher concentrations for growth at higher temperatures. Accurate
monoubiquitinated on lys-147; may give a specific tag for epigenetic transcriptional activation (by similarity). Erroneous
probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits (by similarity). Possibly Erroneous
organized into a structure (processome or rna degradosome) containing a number of rna-processing enzymes. Inconsistent
involved in the formation of the nuclear envelope and of the transitional endoplasmic reticulum (ter). Inconsistent
this methionine-rich region is probably important for copper tolerance in bacteria (by similarity). Erroneous
they have identical ligand binding properties but different coupling properties with g proteins. Possibly Erroneous
3-carboxy-2-hydroxy-4-methylpentanoate + nad(+) = 3-carboxy-4-methyl-2- oxopentanoate + nadh. Accurate
this is a conceptual translation; two frameshifts had to be introduced to produce this orf. Erroneous
component of the infraciliary lattice (icl) and the ciliary basal bodies (by similarity). Possibly Erroneous
catalyzes the methylation of c-11 in precorrin-4 to form precorrin-5 (by similarity). Possibly Erroneous
on the 2d-gel the determined pi of this unknown protein is: 6.2, its mw is: 28 kda. Accurate
heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit (by similarity). Accurate
this viral protein may be involved in the regulation of the complement cascade. Inconsistent
two forms; long (shown here) and short; are produced by alternative splicing. Inconsistent
assembles at the inner surface of the cytoplasmic membrane (by similarity). Too Many Results
1-aminocyclopropane-1-carboxylate + o2 = ethylene + hcn + co(2) + 2 h(2)o. Accurate
bind preferentially single-stranded dna and unwind double stranded dna. Inconsistent
involved in the regulation of hydrogenase expression (by similarity). Erroneous
may have an essential function in lipopolysaccharides biosynthesis. Erroneous
rch(2)nh(2) + h(2)o + acceptor = rcho + nh(3) + reduced acceptor. Accurate
subunit 1 binds to the primer-template junction (by similarity). Inconsistent
to immunoglobulin and major histocompatibility complex domain. Too Many Results
isoform 3: membrane; multi-pass membrane protein (potential). Possibly Erroneous
the beta subunit seems to be encoded by a multigene family. Erroneous
atp + adenylylsulfate = adp + 3–′phosphoadenylylsulfate. Inconsistent
an aryl sulfate + a phenol = a phenol + an aryl sulfate. Erroneous
peptidyl-l-amino acid + h(2)o = peptide + l-amino acid. Possibly Erroneous
in the c-terminus to yeast sla2 and c.elegans zk370.3. Erroneous
mediates e2-dependent ubiquitination (by similarity). Accurate
villin is a ca(2+)-regulated actin-binding protein. Inconsistent
atp + undecaprenol = adp + undecaprenyl phosphate. Accurate
aminoacyl-peptide + h(2)o = amino acid + peptide. Inconsistent
to the calcitonin and to the secretin receptors. Erroneous
heterodimer of an alpha chain and a beta chain. Too Many Results
requires ca2+ and mn2+ ions for full activity. Inconsistent
contains 1 immunoglobulin-like v-type domain. Too Many Results
belongs to family 13 of glycosyl hydrolases. Too Many Results
acts as a transglycosylase (by similarity). Erroneous
nuclear effector molecule (by similarity). Possibly Erroneous
involved in carbon catabolite repression. Erroneous
q9vy42:cg1461; 1; ebi-194476, ebi-127720; Erroneous
contains 6 ldl-receptor class b domains. Erroneous
ring cleavage of 2,3-dihydroxybiphenyl. Possibly Erroneous
not expected to have protease activity. Accurate
secreted in hemolymph (by similarity). Accurate
interacts with rad51 (by similarity). Accurate
endplasmic reticulum membrane bound. Accurate
associated with the plasma membrane. Accurate
does not have a catalytic activity. Possibly Erroneous
belongs to the eae/invasin family. Erroneous
interacts with cyclin g in vitro. Possibly Erroneous
self; 1; ebi-190958, ebi-190958; Possibly Erroneous
binds 1 nickel ion per monomer. Accurate
binds 1 magnesium per subunit. Inconsistent
clavulanic acid biosynthesis. Accurate
belongs to the ycf50 family. Accurate
inhibited by acetazolamide. Erroneous
involved in tumorigenesis. Accurate
acetyltransferase enzyme. Possibly Erroneous
phosphorylates ppp1r12a. Possibly Erroneous
detected at low levels. Accurate
interacts with trim28. Accurate
contacts protein l19. Erroneous
interacts with gcn5. Accurate
may self-associate. Accurate
secreted in milk. Too Many Results
heme-thiolate. Accurate
adipocytes. Accurate
nadp. Accurate
nuclear. Too Many Results
p. Too Many Results
25. Too Many Results
1. Too Many Results
3. Too Many Results
2. Too Many Results
venom. Inconsistent
roots. Inconsistent
leaf. Inconsistent

All of sentences analysed, and their corresponding classification. Sentences have been stored in lowercase to allow for case insensitive comparison. For further information, including the entries affected by these sentences, please see the authors website.