Table 1.

RNA/DNA oligonucleotide sequences

Oligo name	RNA/DNA	Sequence (5` - 3`)
let-7-a1 guide	RNA	P-UGAGGUAGUAGGUUGUAUAGUU
let-7-a1 passenger	RNA	P-CUAUACAAUCUACUGUCUUUCC
let-7-a1 mutant guide	RNA	P-UGCGUUAGUAGGUUGUAUAGUU
let-7-a1 mutant passenger	RNA	P-CUAUACAAUCUACUGUCGUUCC
siluc2 siRNA guide	RNA	GAAGUGCUCGUCCUCGUCCUU
siluc2 siRNA passenger	RNA	GGACGAGGACGAGCACUUCUU
MS2	DNA	AXGTCGACCTGCAGACAXGGGTGATCCTCAXGTTTTCTAGGCAATXA
C-MS2	DNA	P-TAATTGCCTAGAAAACATGAGGATCACCCATGTCTGCAGGTCGACAT

P – 5` Phosphate, X - amine modified deoxy-uridine, underlined bases represent differences between wild-type and mutant sequences