Fig. 6.

Effects of anti-T. cruzi therapy on G-CSF-mediated control of myocardial pathology. T. cruzi-infected mice were treated with BZ at 4 and 6 months post-infection, followed by administration of G-CSF at 10 months post-infection. Paraffin-embedded tissue-sections were subjected to H&E staining, and inflammatory index calculated as detailed in the Materials and methods (^#p < 0.05, vs. infected, ^ξp < 0.05, vs. infected/BZ-treated (6-mo pi). I: infected, I + GCSF: infected/G-CSF treated. I + BZ(4 m)/I + BZ(6 M): infected/BZ-treated at 4 and 6 mo pi, respectively. I + BZ (4 m) + GCSF/I + BZ(6 m) + GCSF: infected/BZ-treated at 4 and 6 mo pi and then treated with G-CSF at 10 mo pi.