Table 1.
Quantification of PICALM and AP180 in the frontal cortex
| Protein (pmol/mg tissue protein)a | ||||||
|---|---|---|---|---|---|---|
| Donor ID | #1 | #5 | #12 | #13 | #14 | #18 |
| PICALM+AP180 | ||||||
| Q1 | 7.1 ± 0.3 | 6.7 ± 0.4 | 6.2 ± 1.0 | 6.7 ± 0.2 | 7.5 ± 0.3 | 7.0 ± 0.4 |
| consensus | 6.9 ± 0.4 | |||||
| PICALM | ||||||
| Q3 | 0.82 ± 0.14 | 0.64 ± 0.17 | 0.51 ± 0.27 | 0.81 ± 0.43 | 0.63 ± 0.38 | 0.50 ± 0.20 |
| Q4 | 0.79 ± 0.40 | 0.62 ± 0.12 | 0.57 ± 0.24 | 0.61 ± 0.20 | 0.53 ± 0.30 | 0.44 ± 0.05 |
| consensus | 0.62 ± 0.13 | |||||
a
The concentration was calculated for three biological replicates by monitoring three transitions per individual peptide and presented as mean ± SD. For the consensus, the data for Q1 from different donors and data for Q3 and Q4 from different donors were combined and presented as mean ± SD. The monitored transitions are summarized in Supplementary Table S2.