Table 6.
Variable | Group | n | Median OS in months (95% CI) |
P-value
|
|
---|---|---|---|---|---|
Univariate | Multivariate | ||||
Age (years) | <50 | 34 | 14.1 (11.8–16.5) | 0.56 | NA |
≥50 | 26 | 15.2 (13.3–17.2) | |||
Sex | Female | 26 | 13.4 (7.3–19.5) | 0.038 | 0.018 |
Male | 34 | 15.3 (13.2–17.4) | |||
Presurgery volume (cc) | <30 | 24 | 15.3 (13.6–17) | 0.035 | 0.032 |
30 to <50 | 22 | 13 (10.2–15.8) | |||
≥50 | 14 | 12.2 (4.3–20.1) | |||
Surgery extent | Near total | 14 | 15.2 (12.8–17.7) | 0.18 | 0.057 |
Subtotal | 24 | 13.4 (10.1–16.7) | |||
Biopsy | 22 | 14.1 (12.3–16) | |||
Postsurgery residual volume (cc) | ≤10 | 18 | 15.3 (14.1–16.5) | 0.029 | 0.008 |
>10 | 42 | 13 (10.3–15.6) | |||
KPS | ≤80 | 46 | 13.4 (10.9–15.9) | 0.073 | 0.01 |
>80 | 14 | 17.2 (12.3–22.2) | |||
Posttreatment (radio/chemotherapy) volume | ≤10 | 26 | 15.3 (13.8–16.8) | 0.03 | 0.031 |
>10 | 34 | 13 (9.5–16.5) | |||
Treatment arm | I | 30 | 12.3 (7.7–16.9) | 0.83 | NA |
II | 30 | 14.3 (14–14.7) | |||
Response to treatment | No | 40 | 14.3 (12.3–16.4) | 0.89 | NA |
Yes | 20 | 14.3 (11.7–16.8) |
Abbreviations: CI, confidence interval; NA, not applicable (multivariate [Cox regression] analysis included variables with a P-value ≤0.2 in univariate analysis); KPS, Karnofsky Performance Status.