Table II.
In vitro susceptibilities to polycationic peptides.
| Strains (no) | Agent | MIC (μg/ml)
|
||
|---|---|---|---|---|
| Range | 50%a | 90%a | ||
| Escherichia coli (30) | BF II | 0.125–2 | 0.5 | 1 |
| C P1 | 0.125–2 | 0.5 | 2 | |
| IND | 0.5–8 | 2 | 4 | |
| MG II | 0.25–2 | 0.5 | 2 | |
| RNL | 1–32 | 4 | 16 | |
| Pseudomonas aeruginosa (10) | BF II | 1–16 | 8 | 8 |
| C P1 | 2–32 | 8 | 16 | |
| IND | 4–64 | 16 | 64 | |
| MG II | 4–16 | 8 | 16 | |
| RNL | 8–64 | 16 | 32 | |
| MS Staphylococcus aureus (10) | BF II | 0.5–8 | 2 | 8 |
| C P1 | 8–64 | 16 | 64 | |
| IND | 1–8 | 4 | 8 | |
| MG II | 8–64 | 16 | 64 | |
| RNL | 0.25–8 | 2 | 8 | |
| MR Staphylococcus aureus (10) | BF II | 1–8 | 2 | 8 |
| C P1 | 16–64 | 32 | >64 | |
| IND | 2–16 | 8 | 16 | |
| MG II | 8–64 | 32 | 64 | |
| RNL | 1–8 | 4 | 8 | |
a
MICs at which 50 and 90% of the strains are inhibited; MS, methicillin-susceptible strains; MR, methicillin-resistant strains; MIC, minimun inhibitory concentration; BF II, buforin II; C P1, ceropin P1; IND, indolicidin; MG II, magainin II; RNL, ranalexin.