Figure 4. Orientation of the 1,2,3-triazole groups of 6 and 7.

Superimposition of (a) 5 (cyan) and 6 (green) and (b) 5 and 7 (pale blue) as bound within the N8:5, N8:6, and N8:7 complexes, respectively. The triazole nitrogen atoms (indicated by an arrow) of 6 overlay with the guanidino moiety of 5, whereas in N8:7 this group is rotated approximately 135°, leading to a repositioning of the alkyl-alcohol functional group.