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. 2013 Nov 1;19(13):1481–1493. doi: 10.1089/ars.2012.4537

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Copyright 2013, Mary Ann Liebert, Inc.

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FIG. 4. — Transcripts encoding Nrf2 and downstream targets are decreased in YG8R DRGs and correlated with frataxin levels. (A–H) Correlation analysis of the frataxin transcript levels with Nrf2 (A), Cat (B) Gclc (C), Gclm (D), Hmox (E), Sod1 (F), Sod2 (G), and TxnRD1 (H). n=12 mice. Statistics were generated using GraphPad Prism software v4.02 for Windows (GraphPad Software). Cat, catalase; Gclc, glutamate–cysteine ligase, catalytic subunit; Gclm, glutamate–cysteine ligase, modifier subunit; Hmox, heme oxygenase; Nrf2, nuclear factor-E2-related factor-2; Sod1, Cu/Zn superoxide dismutase; Sod2, Mn superoxide dismutase; TxnRD1, thioredoxin reductase 1.