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A) Schematic representation of DISP1 protein and the position of p.Ala1471Gly mutation. B) The protein sequence alignment by ClustalW2 (http://www.ebi.ac.uk/Tools/clustalw2/index.html) in different species shows that wild type alanine (A) at position 1471 is evolutionarily conserved. Conserved amino acids compared to humans are indicated in red.
