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R175H does not induce apoptosis by DRAM overexpression. (a) and (b) Saos-2Tet-p53-R175H or SF126Tet-p53-R175H was transfected with plasmid encoding DRAM and their ability to induce apoptosis was analyzed by flow cytometry 48 h after Dox treatment. ΔsubG1 is presented as mean ± SD.
