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. 2013 Feb 3;2(1):1–10. doi: 10.1002/cam4.39

Figure 5.

Figure 5

The influence of DRAM knockdown on the ability of S121F to induce apoptosis. (a) and (b) Saos-2Tet-p53-S121F or SF126Tet-p53-S121F was infected with lentivirus containing DRAM shRNA. The DRAM mRNA levels were analyzed by qRT-PCR 24 h after Dox treatment. Data are presented as the mean ± SD. NSC, nonsilencing control. (c) and (d) Ability to induce apoptosis was analyzed by flow cytometry 36 or 30 h after Dox treatment in (a) or (b), respectively. The subG1 fractions are presented as mean ± SD (%).