Figure 4.

A kinetic model recapitulates biophysical data. (A) Stimulation with the experimentally observed temperature change induced by an IR laser pulse induces C_m behavior similar to the biophysical results. Here, the model transition rates are set to give a V_h of −71 mV. (B) Plots of NLC show rightward shifts along the voltage axis as a result of temperature increase. (C) Rates of V_h shift are comparable to biophysical data and directly follow temperature alterations. (D) Voltage at reversal of ΔC_m is related to V_h. Note that ΔC_m goes back to zero, in contrast to the biophysical data, when C_lin is not temperature sensitive (closed circles). Including temperature dependence for C_lin results in an offset similar to the biophysical data (open circles, curly brackets). To see this figure in color, go online.