Table 1.
Basis of equation and sex | Serum creatinine | CYC | Equation for estimating GFR |
---|---|---|---|
Cockcroft–Gault equation13 | |||
(140 − Age) × Weight ÷ SC ÷ 72 × [0.85 if female] × 1.73 ÷ BsA | |||
Re-expressed 4-variable MDRD equation14 | |||
175 × SC−1.154 × Age−0.203 × [0.742 if female] × [1.212 if Black] | |||
CKD-EPI creatinine equation15 | |||
Female | ≤0.7 | 144 × (SC ÷ 0.7)−0.329 × 0.993Age [× 1.159 if Black] | |
Female | >0.7 | 144 × (SC ÷ 0.7)−1.209 × 0.993Age [× 1.159 if Black] | |
Male | ≤0.9 | 141 × (SC ÷ 0.9)−0.411 × 0.993Age [× 1.159 if Black] | |
Male | >0.9 | 141 × (SC ÷ 0.9)−1.209 × 0.993Age [× 1.159 if Black] | |
CKD-EPI creatinine–cystatin C equation5 | |||
Female | ≤0.7 | ≤0.8 | 130 × (SC ÷ 0.7)−0.248 × (CYC ÷ 0.8)−0.375 × (0.995)Age × [1.08 if Black] |
>0.8 | 130 × (SC ÷ 0.7)−0.248 × (CYC ÷ 0.8)−0.711 × (0.995)Age × [1.08 if Black] | ||
Female | >0.7 | ≤0.8 | 130 × (SC ÷ 0.7)−0.601 × (CYC ÷ 0.8)−0.375 × (0.995)Age × [1.08 if Black] |
>0.8 | 130 × (SC ÷ 0.7)−0.601 × (CYC ÷ 0.8)−0.711 × (0.995)Age × [1.08 if Black] | ||
Male | ≤0.9 | ≤0.8 | 135 × (SC ÷ 0.9)−0.207 × (CYC ÷ 0.8)−0.375 × (0.995)Age × [1.08 if Black] |
>0.8 | 135 × (SC ÷ 0.9)−0.207 × (CYC ÷ 0.8)−0.711 × (0.995)Age × [1.08 if Black] | ||
Male | >0.9 | ≤0.8 | 135 × (SC ÷ 0.9)−0.601 × (CYC ÷ 0.8)−0.375 × (0.995)Age × [1.08 if Black] |
>0.8 | 135 × (SC ÷ 0.9)−0.601 × (CYC ÷ 0.8)−0.711 × (0.995)Age × [1.08 if Black] |
Abbreviations: BSA, body surface area; CYC, cystatin C; CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; GFR, glomerular filtration rate; MDRD, Modification of Diet in Renal Disease; SC, serum creatinine.