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. 2013 Oct 17;7:363. doi: 10.3332/ecancer.2013.363

Table 1. Various risk assessment models and the factors considered in assessing the risk of breast cancer.

Gail model Claus model BRCAPRO model Tyrer–Cuzick model BOADICEA model
  • Age of the person

  • Age at menarche

  • Age at first live birth

  • Breast biopsies (AH)

  • Family history

    • -

      First-degree relatives

  • Age of the person

  • Age at menarche

  • Age at first live birth

  • Family history

    • -

      First-degree relatives

    • -

      Second-degree relatives

  • Age of the person

  • Family history

    • -

      First-degree relatives

    • -

      Second-degree relatives

    • -

      Third-degree relatives

    • -

      Age at onset of breast cancer

    • -

      Bilateral breast cancer

    • -

      Ovarian cancer

    • -

      Male breast cancer

  • Age of the person

  • Body mass index

  • Age at menarche

  • Age at first live birth

  • Age at menopause

  • Hormone replacement therapy use

  • Breast biopsies (ADH, LCIS)

  • Family history

    • -

      First-degree relatives

    • -

      Second-degree relatives

    • -

      Age at onset of breast cancer

    • -

      Bilateral breast cancer

    • -

      Ovarian cancer

  • Age of the person

  • Family history

    • -

      First-degree relatives

    • -

      Second-degree relatives

    • -

      Third-degree relatives

    • -

      Age at onset of breast cancer

    • -

      Bilateral breast cancer

    • -

      Ovarian cancer

    • -

      Male breast cancer

AH, atypical hyperplasia; LCIS, lobular carcinoma in situ; BOADICEA, breast and ovarian analysis of disease incidence and carrier estimation algorithm.